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. 2014 Dec 16;3(4):340–351. doi: 10.3390/microarrays3040340

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Average of the fraction of genes shared by two lists of differentially expressed genes (overlap) as a function of the sample size using the Multiple Myeloma dataset divided according to (A) Overall Survival Milestone Outcome (OS-MO) and (B) Event Free Survival Milestone Outcome (EFS-MO). Each list of differentially expressed genes is composed by the top 100 genes chosen according to different ranking methods, i.e., t-test, SAM and LIMMA (preprocessed by the RMA method), and our approach (median t-value) which does not require a preprocessing algorithm. The average value of the overlap between the lists is calculated over 100 lists chosen randomly.