TABLE 3.
Clinical reports on STIC at RRSO
| Author | No. RRSO Cases |
No. STIC Cases |
Age Range (Years) |
Inclusion Criteria | Pathology Protocol |
|---|---|---|---|---|---|
| Lamb*16 | 113 | 4 (3.5%) | 47–65 | BRCA mutation carrier or high-risk personal/family history |
2–3 mm sectioning for 23/30 patients |
| Carcangiu12 | 50 | 3 (6%) | 48–61 | BRCA mutation carrier | 2–12 slides reviewed per tube or ovary, for 20 patients the tubes and ovaries were submitted in their entirety |
| Powell23 | 111 | 4 (3.6%) | 43–52 | BRCA mutation carrier | Rigorous pathology protocol |
| Callahan14 | 122 | 3 (2.5%) | 44–66 | BRCA mutation carrier | 2–3 mm sectioning for patients before 2/2005, SEE-FIM 2/2005 and after |
| Finch8 | 159 | 1 (0.6%) | 64 | BRCA mutation carrier | 2 mm sectioning for 91/159 patients |
| Manchanda19,20 | 308 | 9 (3%) | 40–67 | BRCA mutation carrier or high risk personal/family history |
2–3 mm sectioning for all patients |
| Wethington (current study) |
593 | 12 (2%) | 39–77 | BRCA mutation carrier or high-risk personal/family history |
SEE-FIM |
| Total | 1456 | 36 (2%) | 39–77 |