Table 1.

Patient Characteristics

Characteristic	Patients With Topoisomerase IIα Assessment (n = 624)	All Treated Patients (n = 1572)	P (assessed to all treated)
Age, years
Median	50	49	.13
Range	22-77	22-81
Tumor size, cm
Median	2.6	2.6	.26
Range	0.3-12.0	0.1-12.0
No. of positive nodes
Median	3.0	3.0	.17
Range	1-54	1-54
Premenopausal, %	39.7	43	.12
Receptor positive, %	72.3	72	.86
Dose of CAF, %
Low	32	33
Moderate	33	33	.82
High	35	34

NOTE. Age, tumor size and No. of positive nodes were compared using the Wilcoxon rank–sum test. The χ² test was used to test for differences in percentage premenopausal, receptor positive, and in the three dose levels of CAF.

Abbreviation: CAF, cyclophosphamide, doxorubicin, and fluorouracil.