Table 3.
Accelerated Phase Features at Baseline and Evolution During Follow-Up
| Accelerated Phase Feature | Patients |
Median Survival Time (months) | |
|---|---|---|---|
| No. | % | ||
| Present at diagnosis (baseline) | |||
| Blood or marrow blasts ≥ 10% | 14 | 4 | 12 |
| Platelets < 50 × 109/L | 50 | 14 | 14 |
| Abnormal Chromosome 17 | 2 | < 1 | < 6 |
| Multiple features* | 11 | 3 | 6 |
| Evolution of accelerated feature during follow-up | |||
| Blood or marrow blasts ≥ 10% | 26 | 12 | |
| Platelets < 50 × 109/L | 20 | 15 | |
| Abnormal chromosome 17 | 6 | 6 | |
The baseline category multiple features included six patients with abnormal chromosome 17 and thrombocytopenia, four patients with increased blasts and thrombocytopenia, and one patient with all three features.