Table 2.

Proposed Monitoring by FISH and Molecular Studies in Patients in Durable Complete Cytogenetic Response

FISH	BCR-ABL Ratio International Standard (%)	Interpretation
Negative	≤ 0.1	Excellent response; 6-month follow-up
Negative	0.1-1	Follow-up every 6 months, follow-up in 3 months if one log ↑ of BCR-ABL ratio; assess compliance
Positive	≤ 0.1	FISH or molecular tests are false positive or false negative; repeat in 3 months
Negative	> 1	FISH or molecular tests are false positive or false negative; repeat in 3 months
Positive	> 1	Check marrow and cytogenetics; possible relapse; assess compliance

Abbreviation: FISH, fluorescent in situ hybridization.