Table 4.
Referral and hazard of repeated poisoning—Cox regression analysis
| n | Events | Crude | Adjusted | |||||
|---|---|---|---|---|---|---|---|---|
| Hazard ratio | 95 % CI | p | Hazard ratio | 95 % CI | p | |||
| Age | ||||||||
| 16–22 yearsa | 683 | 50 | ||||||
| 23–27 years | 437 | 54 | 1.7 | 1.2–2.5 | 0.005 | 1.1 | 0.74–1.7 | 0.62 |
| Sex | ||||||||
| Femalesa | 518 | 37 | ||||||
| Males | 602 | 67 | 1.6 | 1.1–2.4 | 0.021 | 1.2 | 0.76–1.8 | 0.50 |
| Main toxic agent | ||||||||
| Ethanola | 715 | 27 | ||||||
| Opioids | 170 | 48 | 9.2 | 5.7–14.8 | <0.001 | 8.5 | 5.0–14.3 | <0.001 |
| Benzodiazepines | 89 | 12 | 3.9 | 2.0–7.7 | <0.001 | 3.8 | 1.8–7.8 | <0.001 |
| Central stimulants | 49 | 6 | 3.5 | 1.4–8.5 | 0.006 | 3.2 | 1.3–8.0 | 0.012 |
| GHB | 60 | 8 | 3.7 | 1.7–8.1 | 0.001 | 3.4 | 1.5–7.9 | 0.004 |
| Other | 37 | 3 | 2.2 | 0.66 -7.1 | 0.20 | 2.1 | 0.63–6.9 | 0.23 |
| Referral to follow-up | ||||||||
| No referrala | 709 | 55 | ||||||
| Referral | 411 | 49 | 2.0 | 1.4–2.9 | <0.001 | 1.0 | 0.69–1.6 | 0.83 |
Referral to follow-up and hazard of repetition of poisoning in 1120 patients aged 16–27 years presenting with acute poisoning by substances of abuse in 2008 and 2012
There were 104 events (repetitions). One patient was censored due to death, two were censored due to emigration
The hazard ratio for referrals was hardly affected by entering age and sex into the model, but changed when main toxic agent was entered
aReference group