Fig. 4.

Identification of an M. rosenbergii p62. a A schematic annotation of M. rosenbergii p62 (Mrop62) and the sequence alignment of crustacean p62 proteins with p62 of other species from different phyla. Black shading indicates conserved amino acids while grey shading indicates similar amino acids. Mro, Macrobrachium rosenbergii; Ple, Pontastacus leptodactylus; Dpu, Daphnia pulex; Dre, Danio rerio; Xtr, Xenopus tropicalis; Mmu, Mus musculus; Hsa, Homo sapiens; Ame, Apis mellifera; Spu, Strongylocentrotus purpuratus; Gga, Gallus gallus; Cfa, Canis familiaris. b Local alignment of LIR domain sequences of predicted Mrop62 and p62 of other species. c Predicted tertiary structure of Mrop62. The predicted Phox and Bem1p (PB1; amino acid positions 6–96), ubiquitin-associated (UBA; amino acid positions 588–634), and LC3-interacting region (LIR; amino acid positions 534–555) domains of Mrop62 are colored in yellow, purple, and red, respectively