Skip to main content
. 2013 Oct 7;31(31):4014–4021. doi: 10.1200/JCO.2012.47.9949

Fig 2.

Fig 2.

Percent of 1,000 simulated trials in which dose recommended by combined analysis using dose-escalation and -expansion cohorts was same as level recommended by dose-escalation alone, regardless if that is true maximum-tolerated dose (MTD). Within a level is defined as dose ± one level from true MTD; exact is defined as true MTD; other includes dose recommendations that are within two levels from true MTD.