Table 5.
Biological functions and pathways significantly (FDR < 0.05) enriched in the Turquoise module (764 genes) using DAVID
| DAVID functional category | Biological term | Number of genes | FDR adjusted p-value |
|---|---|---|---|
| SP_PIR_Keyword | Acetylation | 195 | 8.22E-44 |
| Phosphoprotein | 210 | 9.16E-19 | |
| Ribonucleoprotein | 51 | 3.63E-17 | |
| Cytoplasm | 138 | 1.17E-16 | |
| Ribosomal protein | 44 | 2.53E-16 | |
| Protein biosynthesis | 20 | 2.24E-06 | |
| Isopeptide bond | 23 | 5.54E-06 | |
| Proteasome | 15 | 8.76E-06 | |
| Ubl conjugation | 29 | 5.80E-05 | |
| Nucleotide-binding | 74 | 3.65E-04 | |
| Wd repeat | 22 | 8.04E-04 | |
| Actin-binding | 17 | 9.48E-04 | |
| Transit peptide | 35 | 4.94E-03 | |
| Chaperone | 17 | 6.61E-03 | |
| Threonine protease | 7 | 8.72E-03 | |
| Methylation | 17 | 1.67E-02 | |
| Initiation factor | 9 | 1.80E-02 | |
| ATP-binding | 50 | 2.43E-02 | |
| Mitochondrion | 47 | 3.18E-02 | |
| Protein transport | 24 | 3.47E-02 | |
| KEGG_Pathway | bta03010:Ribosome | 36 | 3.05E-21 |
| bta03050:Proteasome | 14 | 1.86E-05 | |
| bta04520:Adherens junction | 14 | 1.97E-03 | |
| bta00190:Oxidative phosphorylation | 19 | 5.94E-03 | |
| bta04810:Regulation of actin cytoskeleton | 22 | 2.65E-02 | |
| bta03040:Spliceosome | 16 | 3.95E-02 |