Table 6.
Top biological functions and pathways significantly (p < 0.05) enriched in the Turquoise module with IPA
| IPA category | Biological term | Number of genes | FDR adjusted p-value |
|---|---|---|---|
| Molecular and cellular function | Protein synthesis | 89 | 6.06E-11 |
| Cellular growth and proliferation | 232 | 6.06E-11 | |
| Post-translational modification | 51 | 2.80E-07 | |
| Protein folding | 17 | 7.92E-07 | |
| Cell death and survival | 211 | 1.03E-06 | |
| Canonical pathway | EIF2 signaling | 51 | 5.85E-30 |
| Regulation of eIF4 and p70S6K signaling | 35 | 3.28E-18 | |
| mTOR signaling | 39 | 3.60E-18 | |
| Remodeling of epithelial adherens junctions | 19 | 3.21E-11 | |
| Epithelial adherens junction signaling | 25 | 9.05E-10 |