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Biological plausibility and pleiotropic actions of statin when used to treat/prevent preeclampsia. (HO-1: heme oxygenase-1; sFlt-1: soluble fms-like tyrosine kinase 1; PlGF: placental growth factor; eNOS: endothelial nitric oxide synthase; VEGF: vascular endothelial growth factor; MP: microparticles, EPC: endothelial progenitor cells, hs-CRP: high sensitivity c-reactive protein)
