Table A2.

Multivariate Cox Proportional Hazards Analysis for Overall Survival of Patients With MDS/CMML, All Groups (n = 249)

Variable	P	Hazard Ratio	95% CI
Patient age	.001	1.029*	1.012 to 1.046
High-risk karyotype (IPSS)	< .001	4.310	2.752 to 6.750
Bone marrow blast count	.004	1.049†	1.016 to 1.083
Prior chemotherapy or CMT‡	.41	1.203	0.778 to 1.859
Prior XRT‡	.38	0.781	0.451 to 1.351

Abbreviations: CMT, combined-modality therapy; CMML, chronic myelomonocytic leukemia; IPSS, International Prognostic Scoring System; MDS, myelodysplastic syndrome; XRT, external-beam radiation therapy.

^*Hazard ratio per 1-year increase of age.

^†Hazard ratio per 1% increase in blasts.

^‡Hazard ratio compared with de novo MDS/CMML group.