Table A3.

Multivariate Cox Proportional Hazard Analysis for Overall Survival of Patients With AML, All Groups (n = 201)

Variable	P	Hazard Ratio	95% CI
Patient age	< .001	1.040*	1.025 to 1.055
High-risk karyotype (UKMRC)	< .001	2.710	1.870 to 3.928
Prior chemotherapy or CMT†	.41	1.176	0.801 to 1.728
Prior XRT†	.13	0.626	0.341 to 1.150

Abbreviations: AML, acute myeloid leukemia; CMT, combined modality therapy; UKMRC, United Kingdom Medical Research Council; XRT, external-beam radiation therapy.

^*Hazard ratio per 1-year increase of age.

^†Hazard ratio compared with de novo AML group.