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CONSORT diagram. CMMRD, constitutional mismatch repair deficiency; CRC, colorectal cancer; FAP, familial adenomatous polyposis; FDR, first-degree relative; IBD, inflammatory bowel disease; LFS, Li-Fraumeni syndrome; MAP, MUTYH-associated polyposis; MMR, mismatch repair; SDR, second-degree relative; VUS, variant of uncertain significance.
