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. 2016 Aug 10;7:249. doi: 10.3389/fphar.2016.00249

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Copyright © 2016 Wang, Chan, Zhou, Cui, Yan, Wang, Yan, Di, Wang, Hoi, Shan and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dox inhibited DT-010-induced GRP78 expression in MCF-7 cells. Immunoblots (A) and densitometric analysis (C) of the expression of GRP78 protein were determined after DT-010 treatment in MCF-7 cells. (B) MCF-7 cells were treated with DT-010 for 24 h in the presence or absence of Dox. Representative immunoblots for the expression of GRP78 and β-actin proteins were exhibited. (D) Densitometric analysis showed the expression of GRP78 protein. ^#P < 0.05 vs. Ctrl.