The patient is a 68-year-old woman with stage IV serous ovarian carcinoma treated with bevacizumab from 4/2012-9/2012. In 9/2012, she developed hypertension and mental status changes.
A. MRI Brain FLAIR sequence from 10/9/2012 shows confluent hyperintensities within the supratentorial white matter, predominantly within the posterior temporal and occipital lobes consistent with PRES.
B. MRI Brain FLAIR sequence from 4/4/2013 shows resolution of extensive white matter changes after discontinuation of bevacizumab treatment.