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Weight loss corrects the elevated gut commensal Firmicutes/Bacteroidetes ratio associated with obesity. On Day 26 after dietary intervention (as described in Figure 3), fecal pellet total eubacterial 16S (A) ribosomal RNA (rRNA) and (B) phlya-specific 16S rRNA DNA content was quantitated, and (C) the Firmicutes/Bacteroidetes ratio, relative to that found in the LFD mice, was calculated; n = 8–10 mice per group. ***P ≤ 0.001; ****P ≤ 0.0001.
