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. 2015 Sep 28;1:15035. doi: 10.1038/cddiscovery.2015.35

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Copyright © 2015 Cell Death Differentiation Association

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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H. pylori infection is associated with increased Cx43 expression in human gut tissues. Cx43 was detected (i.e., brown staining) in H. pylori-negative (a and c) and -positive (b and d) gastric mucosa. Blue color indicated nuclear staining by hematoxylin. The black square shows low magnification views of the structures in c and d, respectively (a and b: ×20 ; c and d: ×80). The figure shows one experimental result representative of 5 H. pylori-negative and 11 of H. pylori-positive samples. Statistically significant difference between H. pylori-negative and -positive mucosa was observed (P=0.0256). Fisher’s exact test, H. pylori-positive versus -negative mucosa. Bars represent 50 μm.