Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 29;2:16013. doi: 10.1038/cddiscovery.2016.13

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Cell Death Differentiation Association

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Gene expression profiling. (a) Schematic representations of the gene expression profiling in human OneArray experiments carried out in ARPE-19 cells. (b) Gene ontology (GO) analysis demonstrated differentially expressed pathways between non-light-damaged and light-damaged cells. (c) Gene expression signature of light-damaged ARPE-19 cells in the p53 hypoxia pathway. (d) Quantitative RT-PCR was performed to confirm the results from our GO analysis. mRNA levels were standardized to the control gene β-actin. Results are presented as mean value±S.E.M. (n=3, *P<0.05, ***P<0.001). (e) Western blotting showed upregulation of p-p53 in light-damaged cells. The β-actin loading control is from the same experiment as shown in Figure 5a and is reproduced in this figure for ease of reference.