Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 1;2:16004. doi: 10.1038/cddiscovery.2016.4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Cell Death Differentiation Association

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

NGF plus TRAIL abrogates the tumourigenic activity of TrkA SH-SY5Y cells in vitro. (a) Representative photograph and (b) histogram demonstrating significant inhibition of TrkA SH-SY5Y but not NT SH-SY5Y or pcDNA SH-SY5Y tumourigenic activity in vitro by NGF (100 ng) alone or in combination with TRAIL (200 ng). Results are displayed as the mean (±S.D.) number of tumours in 10×10 magnification fields in triplicate experiments each performed in duplicate (*statistical significance). (c) Representative phase contrast micrographs demonstrating tumour spheroid appearance of TrkA SH-SY5Y cells in vitro in the absence (control) or presence of NGF (100 ng/ml), TRAIL (200 ng/ml) plus NGF (100 ng/ml) or TRAIL (200 ng/ml) alone.