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. Author manuscript; available in PMC: 2016 Aug 18.
Published in final edited form as: Biochemistry. 2015 Aug 5;54(32):4953–4968. doi: 10.1021/acs.biochem.5b00565

Figure 2.

Figure 2

Signaling pathway (A) and activation (B) of PKCα. The abbreviations are given in the text. The C-terminal V5 domain is shown in red. DAG-dependent PKCs are constitutively phosphorylated as part of the maturation process, with one site on the kinase activation loop and two sites on the V5 domain.