Table 3.
Recording of Sexual Maturity in Microscopic Observations Data for General Toxicity Studies
| Males | Females | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| All Studies | Somea Studies | No Studies | Total | All Studies | Some Studies | No Studies | Total | ||
| Rodent | # | 15 | 12 | 26 | 53 | 14 | 12 | 27 | 53 |
| % | 28 | 23 | 49 | 26 | 23 | 51 | |||
| Dog | # | 28 | 8 | 12 | 48 | 18 | 9 | 21 | 48 |
| % | 58 | 17 | 25 | 38 | 19 | 44 | |||
| NHP | # | 32 | 6 | 6 | 45 | 19 | 10 | 15 | 44 |
| % | 71 | 13 | 13 | 43 | 23 | 34 | |||
‘Some’ includes a composite of categories including ‘specific study types’, ‘based on pharmacology/target’, ‘triggered by previous findings’, and ‘only if the NHP is the only toxicology species used’.