Table 1. Baseline Demographics and Clinical Factors of Study Subjects (N = 241).
| CRA (n = 45) | Non-CRA (n = 196) | p—value | |
|---|---|---|---|
| Age at diagnosis (years)a | 61.1 ± 13.1 | 52.3 ± 12.2 | < 0.001 |
| Alcohol use, n (%) | 0.387b | ||
| Non drinker | 45 (100) | 188 (95.9) | |
| Social drinker | 0 (0) | 6 (3.1) | |
| Heavy drinker | 0 (0) | 2 (1.0) | |
| Cigarette smoking, n (%) | 0.786b | ||
| Never smoker | 44 (97.8) | 189 (96.4) | |
| Ex-smoker | 0 (0) | 2 (1.0) | |
| Current smoker | 1 (2.2) | 5 (2.6) | |
| Family history of CRC, n (%) | 0.512 | ||
| Presence | 1 (2.2) | 2 (1.0) | |
| Absence | 44 (97.8) | 194 (99.0) | |
| Type of gynecologic disease, n (%) | 0.664 | ||
| Cervical cancer | 28 (62.2) | 134 (68.4) | |
| Endometrial cancer | 17 (37.8) | 59 (30.1) | |
| Others | 0 (0) | 3 (1.5) | |
| Body mass index (kg/m²)a | 24.8 ± 3.2 | 23.9 ± 3.6 | 0.125 |
| Fasting plasma glucose (mg/dL)a | 102.7 ± 31.7 | 97.5 ± 19.9 | 0.293 |
| Serum triglyceride (mg/dL)a | 116.8 ±61.6 | 97.2 ± 49.9 | 0.025 |
| Serum total cholesterol (mg/dL)a | 180.9 ± 39.8 | 177.8 ± 37.1 | 0.619 |
| Background colonic 18F-FDG uptake, n (%) | 0.013b | ||
| Grade 1 | 9 (20.0) | 63 (32.1) | |
| Grade 2 | 12 (26.7) | 69 (35.2) | |
| Grade 3 | 22 (48.9) | 60 (30.6) | |
| Grade 4 | 2 (4.4) | 4 (2.0) |
CRA, colorectal adenoma; non-CRA, non-colorectal adenoma; CRC, colorectal cancer; 18F-FDG, 18F-fluoro-2-deoxy-D-glucose.
aMean ± standard deviation
b trend p value by linear-to-linear association analysis