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. 2016 Aug 10;11(8):e0160573. doi: 10.1371/journal.pone.0160573

Table 2. Immune-Related ICD-9 categories selected for further analysis.

ICD-9 General Classification ICD-9 Code Category (Code: Category Description) Nearest Genes
Endocrine, nutritional and metabolic diseases, and immunity disorders 250: Diabetes mellitus, Type 1 LOC645266, MTCO3P1, HLA-DRA, HLA-DQB2, HLA-DOB, DDC, DDC, LOC100129427, HLA-DMA, HCG23, C6orf10, MIR588, CAST, EPHA5, LOC645321, SERPINB11, KC6, FLJ30679, PRELID1P1, RPS4XP9, THEMIS, HIST1H1T
273: Disorders of plasma protein metabolism LOC100996339, ESRRG
Diseases of the nervous system 331: Other cerebral degenerations QRSL1
340: Multiple sclerosis MYT1L, IRF4
357: Inflammatory and toxic neuropathy GTDC2, RAB38, LOC100129160
Diseases of the sense organs 373: Inflammation of eyelids USH2A, MAP4K4
Diseases of the respiratory system 461: Acute sinusitis CNTNAP2, ANKS1A
465: Acute upper respiratory infections of multiple or unspecified sites RPL23AP54, ZZEF1, ANK3
466: Acute bronchitis and bronchiolitis CLSTN2, LOC100129949
472: Chronic pharyngitis and nasopharyngitis DAP3P2, DCAF17, LOC100287243, METTL8, TAF3, KIAA1217
473: Chronic sinusitis ANK3, TRPS1, KSR1, RBM17
477: Allergic rhinitis KCNK3,VAV3-AS1,PADI4,MED13,KIRREL3,TOX,FTLP7
482: Other bacterial pneumonia TLR6, LOC645481
491: Chronic bronchitis SDC4,RPS2P9, SYS1-DBNDD2,PITX2,SYS1,SYS1-DBNDD2,XCR1
492: Emphysema GABRA4
493: Asthma TPD52L1, CAST, WDR11
515: Postinflammatory pulmonary fibrosis SLC16A10,FRMD6-AS2,LOC100506923,ADIPOR1
Diseases of the digestive system 556: Ulcerative colitis BTF3L4P3
571: Chronic liver disease and cirrhosis RSBN1, RFX3, CTIF, PHTF1
577: Diseases of pancreas LCE1B, NTRK3-AS1
Diseases of the genitourinary system 584: Acute renal failure FAM205B, LACC1, DGKZP1, E2F3, FAM205A
585: Chronic kidney disease STXBP4, LOC100996324, CCDC148, RPL13AP25, BMP2, RRP15
586: Renal failure PLK2, LOC100507162
595: Cystitis SDK1, DNTTIP2
Diseases of the skin and subcutaneous tissue 692: Contact dermatitis and other eczema MB21D2
695: Erythematous conditions SRRM4, PRDM15, VDR, INTS6, FGFR3P3
Diseases of the musculoskeletal system and connective tissue 714: Rheumatoid arthritis and other inflammatory polyarthropathies MTCO3P1, HLA-DRA, NOTCH4, TNIP1, IL6, HLA-DRB1, C6orf10, HLA-DRB9
715: Osteoarthrosis and allied disorders BRD2, SEMA6A, FLJ42102, RNY4P22, TNFSF8, KIAA1919, BACH2, AKT3, SDHAP3, ZBTB38, CAMK1G, PRDM1, U2SURP, RETNLB, ANXA6
716: Other and unspecified arthropathies IL23R, GPX3, TRNAS13, ZNF192P2, AGPAT4, QKI, ENTPD7, GJD4
719: Other and unspecified disorders of joint TCF4, LOC100288337, TBX3