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. 2016 Aug 10;12(8):e1005774. doi: 10.1371/journal.ppat.1005774

Fig 1. CXCL10/IP-10 dynamics in blood before HIV-1 infection and during the early infection, and its impact on the CD4 T-cells count.

Fig 1

IP-10 levels were determined in sera from HIV+ individuals enrolled in the Amsterdam Cohort Studies on HIV/AIDS. A. Plasma IP-10 levels. The numbers of patients per group are indicated. B. Longitudinal follow-up of the same 16 individuals. C. Positive correlation between IP-10 concentrations and viremia at PHI. D. Positive correlation between IP-10 concentrations and viremia at M3 post SC. E. Impact of pre-infection blood IP-10 concentrations on the CD4 T-cells count after seroconversion. F. Impact of M3 blood IP-10 concentrations on the CD4 T-cells count after seroconversion. E and F: Kaplan Meier survival analysis. Pre-inf. = Pre-infection (median 11 months before seroconversion), PHI = Primary HIV-1 infection, M3 and M6 = 3 and 6 months post seroconversion. * p<0.05, ** p<0.001, **** p<0.00001