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. 2016 Aug 10;12(8):e1005774. doi: 10.1371/journal.ppat.1005774

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© 2016 Ploquin et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 8 — (a) confocal image of a jejunum section stained for CD68 (green), IP-10 (red) and total nucleus (blue). The picture represents the distribution of IP-10+ cells in jejunum of chronically infected macaques (240 dpi) (representative picture for one animal out of 3 animals studied). IP-10+ cells were found in the lamina propria around and in the villi as well as at the top of the villi. Most IP-10+ cells were CD68 negative. A fraction of CD68+ cells produced IP-10. Cells were often organized in clusters. (B) Magnification showing IP-10+ cells negative for CD68 found at the bottom of the villus. The morphology evoke T cells. (C) Magnification showing IP-10+ positive for CD68+. (D) Magnification showing IP-10+ cells organized in a cluster. Many IP-10+ cells in these clusters were CD68+. Pictures were obtained using a leica SP8 confocal microscope. All pictures were analyzed with ImageJ software.