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Passively operated microfluidic device for islet secretion sampling and imaging. (A) Device layout, including an image of a trapped islet. (B) Hand-held apparatus for secretion sampling with no electrical components. (C) Insulin adsorption was prevented by dynamic coating with BSA in the microchannel (white bars) as well as in the reservoir (gray bars), by including 0.1% BSA in the media. Error bars represent standard deviations.
