Table 2.
Performance characteristics of each hematocrit determination method when applied to the clinical model.
| Incompatible RBC Cut-off limit | ||||||
|---|---|---|---|---|---|---|
| 10 mL | 15 mL | 20 mL | 30 mL | 40 mL | ||
| Advia | Sensitivity | 100% | 100% | 100% | ND | ND |
| Specificity | 59% | 89% | 96% | 99% | 99% | |
| Positive Predictive Value | 10% | 23% | 33% | 0% | 0% | |
| Negative Predictive Value | 100% | 100% | 100% | 100% | 100% | |
| Preventable RBC reductions | 39% | 10% | 4% | 1% | 1% | |
| Sysmex | Sensitivity | 100% | 100% | 100% | ND | ND |
| Specificity | 82% | 95% | 98% | 98% | 99% | |
| Positive Predictive Value | 19% | 38% | 50% | 0% | 0% | |
| Negative Predictive Value | 100% | 100% | 100% | 100% | 100% | |
| Preventable RBC reductions | 18% | 5% | 2% | 2% | 1% | |
| Abbott | Sensitivity | 100% | 100% | 100% | ND | ND |
| Specificity | 80% | 91% | 97% | 98% | 99% | |
| Positive Predictive Value | 17% | 27% | 40% | 0% | 0% | |
| Negative Predictive Value | 100% | 100% | 100% | 100% | 100% | |
| Preventable RBC reductions | 20% | 8% | 3% | 2% | 1% | |
| Coulter | Sensitivity | 100% | 100% | 100% | ND | ND |
| Specificity | 28% | 80% | 92% | 96% | 99% | |
| Positive Predictive Value | 6% | 14% | 20% | 0% | 0% | |
| Negative Predictive Value | 100% | 100% | 100% | 100% | 100% | |
| Preventable RBC reductions | 69% | 20% | 8% | 4% | 1% | |