. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: J Occup Environ Med. 2016 Aug;58(8):753–759. doi: 10.1097/JOM.0000000000000784

Table 3.

Association of gene variants with ICD

Gene	Position	Location	SNP	Genotype	N	Mean	(95% CI)	P (adjusted)
Gene	Position	Location	SNP	Genotype	N	Mean	(95% CI)	ADD	DOM	REC
EGF	−175	intron	rs10029654	GG	114	0.64	0.55-0.73
				GA	115	0.52	0.43-0.61
				AA	23	0.26	0.07-0.46	0.001326		0.003475
EGFR	−18262	intron	rs12718939	GG	107	0.49	0.39-0.58
				GA	125	0.56	0.47-0.65
				AA	20	0.85	0.68-1.02	0.001159		0.003111
CXCL12	−1125	intron	rs197452	GG	184	0.6	0.53-0.67
				GA	63	0.43	0.3-0.55
				AA	5	0.2	−0.36-0.76	0.002309	0.003884
VCAM1	−1457	intron	rs3917018	GG	129	0.66	0.58-0.74
				GA	92	0.41	0.31-0.52
				AA	31	0.52	0.33-0.7		0.003906

Results are adjusted for hand washing frequency and TEWL measurement on the forefinger; Bold p values represent significance after additional adjustment for age; ADD: Additive genetic model; DOM: Dominant genetic model; REC: Recessive genetic model