. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: J Occup Environ Med. 2016 Aug;58(8):753–759. doi: 10.1097/JOM.0000000000000784

Table 4.

Haplotype based test results

Variable	Chr	BP1	BP2	SNP1	SNP2	Haplotype	F	OR	STAT	P	Genes
NAOH_M	9	87449460	87450766	rs7870666	rs1867283	TA	0.482	3.73	10.1	0.0009999	NTRK2
NAOH_H	7	55105320	55124701	rs12718939	rs6593202	AGA	0.138	2.49	11	0.0008999	EGFR
NAOH_H	7	55105320	55124701	rs12718939	rs6593202	GGG	0.565	0.454	11.3	0.0008999	EGFR

BP1: Physical position of left-most (5′) SNP (base-pair)

BP2: Physical position of right-most (3′) SNP (base-pair)

SNP1: left-most (5′) SNP

SNP2: left-most (3′) SNP

F: Frequency

OR: Estimated odds ratio

STAT: Test statistic (T from Wald test)

P: Empirical p-values from permutation procedures (10,000 permutations)

Haplotypes containing a SNP (rs6593202) that is individually associated with skin irritant response is shown in bold

Results are adjusted for confounders specific to each irritant