Table 1.
Baseline characteristics of enrolled subjects
| CAMP population (n = 461)
|
ALL population (n = 59)¶ | ||||
|---|---|---|---|---|---|
| PD non-taker (n = 93) | PD taker (n = 368)
|
||||
| Tertile 1 | Tertile 2 | Tertile 3 | |||
| Male sex (%) | 62.4 | 57.7 | 66.4 | 61.0 | 52.5 |
| Age (year) | 9.7 (7.6~11.0) | 8.5 (6.8~10.6) | 8.7 (7.1~10.3) | 8.4 (7.1~10.3) | 6.9 (1.4~18.7) |
| Height (cm) | 139.7 (127.3~146.7) | 130.8 (121.0~141.2) | 131.3 (122.9~140.9) | 130.9 (122.2~142.8) | NA |
| BMI (kg/m2) | 17.7 (16.3~21.0) | 17.2 (15.7~19.3) | 17.1 (15.8~19.6) | 16.9 (15.6~18.6) | 15.8 (14.6~18.3) |
| BMD (Z-score) | −0.10 (−0.81~0.53) | −0.16 (−0.62~0.34) | 0.02 (−0.55~0.55) | −0.14 (−0.53~0.39) | NA |
| Vitamin D (ng/mL) | 35.8 (27.7~46.6) | 35.9 (28.8~47.5) | 37.8 (29.6~48.8) | 35.7 (29.3~47.2) | NA |
| Tanner stage (%) | |||||
| I/II/III/IV/V | 65.6/24.7/6.5/3.2/0 | 71.5/22.0/5.7/0/0.8 | 76.2/19.7/1.6/2.5/0 | 74.8/16.3/6.5/2.4/0 | NA |
| Cumulative PD (mg) | 0 | 180.0 (135.0~212.5) | 540.0 (420.0~660.0) | 1430.0 (1100.0~1962.0) | 14640* |
| Race/ethnicity (%) | |||||
| White | 100 | 100 | 100 | 100 | 72.9 |
| Others | 0 | 0 | 0 | 0 | 27.1 |
| Final BMD (Z-score) | −0.08 (−0.83~0.73) | −0.19 (−0.67~0.49) | −0.19 (−0.79~0.62) | −0.36 (−0.81~0.25) | −0.80 (−2.90~4.0) |
Data indicate median (IQR). NA; Not available,
¶
High-dose anti-metabolites arm (n = 29) and low-dose anti-metabolites arm (n = 30),
*
mg/m2/day