Table 3.
Exploration times (in s) with administration of ITI-214 2 h before T1 in the NOR: acquisition. Different dosages of ITI-214 were administered 2 h before T1. The delay interval between the first and second trial was 24 h. n = 20 per experimental condition
| Time PO |
T1 −2 h Vehicle ITI-214 |
T1 −2 h 0.1 mg/kg ITI-214 |
T1 −2 h 0.3 mg/kg ITI-214 |
T1 −2 h 1 mg/kg ITI-214 |
T1 −2 h 3 mg/kg ITI-214 |
T1 −2 h 10 mg/kg ITI-214 |
|---|---|---|---|---|---|---|
| e1 | 28.26 (2.19) | 28.38 (1.86) | 27.55 (1.62) | 27.97 (1.78) | 27.28 (1.74) | 26.21 (1.97) |
| e2 | 25.68 (1.50) | 27.33 (1.48) | 26.10 (1.69) | 29.38 (1.38) | 28.73 (1.62) | 28.15 (1.38) |
No significant differences were found between treatment conditions in exploration times in T1 (e1: F(5,119) = 0.18, n.s.) and in T2 (e2: F(5,119) = 0.94, n.s.)