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. 2016 Aug 11;10:35. doi: 10.3389/fninf.2016.00035

Figure 2.

Figure 2

Voxel vs. world coordinates. Each grid square represents a single sample in the voxel space of the image. The voxel origin (0,0) would be in the upper left corner of the image. The world Y and Z directions are rotated 20⋅ relative to the voxel coordinates. The origin of the world coordinate system would be defined with respect to some anatomical landmark.