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. 2016 Jun 9;6(8):e00504. doi: 10.1002/brb3.504

Figure 3.

Figure 3

Global Structural Network Topology Mediates CADS Scores in d‐TGA Adolescents with and without the ε4 and ε2 ApoE alleles. Results from the mediation analyses demonstrate different paths by which global topology differences mediate CADS scores for d‐TGA adolescents in general (d‐TGA), and for d‐TGA adolescents with the ε2 or ε4 ApoE alleles (APOE2; APOE4). Arrows from the topology metrics to the CADS scores indicate a significant indirect effect (FDR corrected for multiple comparisons with q < 0.05; red = positive, blue = negative). Arrows from the independent variables to the topology metrics indicate difference in topology metrics (red = positive, blue = negative, gray = difference not significant).