Table 2.

Changes in plasma glucose levels, lipids, liver functions, and kidney functions from baseline to week 24.

	Mean (SD) change from baseline to week 24				Mean (95% CI) changes from baseline (SZ-A versus acarbose)	P value
	SZ-A (n = 21)	P value	Acarbose (n = 15)	P value
Plasma glucose levels
Fasting glucose (mmol/L)	1.04 (2.61)	0.083	−0.02 (2.25)	0.976	−0.88 (−2.45 to 0.70)	0.266
Postprandial blood glucose 1 h (mmol/L)	4.10 (5.11)	0.003∗	4.02 (4.92)	0.007∗	0.46 (−2.44 to 3.36)	0.748
Postprandial blood glucose 2 h (mmol/L)	3.84 (5.05)	0.003∗	3.83 (5.83)	0.029∗	0.97 (−2.36 to 4.29)	0.558
HbA1c (%)	0.78 (0.85)	0.000∗	0.83 (1.35)	0.033∗	0.18 (−0.64 to 1.00)	0.652
Lipids
Total cholesterol (mmol/L)	0.06 (1.21)	0.824	−0.01 (0.65)	0.969	0.30 (−0.36 to 0.96)	0.366
Triglycerides (mmol/L)	0.10 (1.17)	0.706	0.31 (0.93)	0.214	0.61 (−0.11 to 1.33)	0.094
HDL (mmol/L)	−0.04 (0.19)	0.386	−0.02 (0.15)	0.527	0.07 (−0.14 to 0.27)	0.513
LDL (mmol/L)	−0.09 (0.72)	0.586	0.06 (0.49)	0.634	0.25 (−0.21 to 0.71)	0.271
Liver functions
Alanine aminotransferase (U/L)	−0.38 (8.39)	0.837	2.07 (14.21)	0.582	−2.53 (−9.77 to 4.70)	0.482
Aspartate aminotransferase (U/L)	0.33 (4.20)	0.720	1.27 (6.15)	0.438	−2.28 (−5.50 to 0.95)	0.160
Kidney functions
Creatinine clearance (mL/min)	2.36 (13.94)	0.447	−2.56 (16.30)	0.553	−3.71 (−17.02 to 9.61)	0.575
Urine acid (mmol/L)	−5.55 (58.59)	0.760	−12.83 (38.79)	0.455	36.50 (−40.03 to 113.03)	0.327

  ^∗ P < 0.05.