Table 3.
Linear Regression of Measured Pao2/Fio2 Ratio, With Potential Covariates
| Predictor | Bivariate |
Multivariate |
||
|---|---|---|---|---|
| Coefficient | P Value | Coefficient | P Value | |
| Imputed Pao2/Fio2a | 1.05 (1.005-1.093) | < .001 | 1.08 (1.03-1.13) | < .001 |
| Vasopressors | 5.27 (0.75-9.78) | .02 | 4.59 (0.16-9.03) | .04 |
| Spo2 | –0.83 (–0.143 to –0.23) | .007 | –0.79 (–1.39 to –0.19) | .01 |
| Fio2 | –6.99 (–28.1 to 14.1) | .51 | NA | NA |
| White race | –0.05 (–5.37 to 5.27) | .99 | NA | NA |
| Black race | –1.27 (–7.73 to 5.20) | .7 | NA | NA |
| Latino ethnicity | –2.12 (–8.54 to 4.31) | .52 | NA | NA |
| Age, y | –0.11 (–0.25 to 0.04) | .14 | NA | NA |
| Peak bilirubin, mg/dL | 0.46 (–0.70 to 1.61) | .44 | NA | NA |
| 24-hour fluid input, mL | 0.0009 (–4.5 to 0.002) | .06 | NA | NA |
| MAP, mm Hg | –0.07 (–0.25 to 0.1) | .42 | NA | NA |
| Tidal volume, mL | 0.005 (–0.02 to 0.03) | .7 | NA | NA |
| PEEP, cm H2O | 0.02 (–0.58 to 0.62) | .95 | NA | NA |
| BMI, kg/m2 | –0.04 (–0.28 to 0.20) | .75 | NA | NA |
| APACHE III, points | 0.04 (–0.04 to 0.12) | .35 | NA | NA |
| Peak hematocrit, % | 0.26 (–0.08 to 0.61) | .14 | NA | NA |
MAP = mean arterial pressure; NA = not applicable. See Table 1 legend for expansion of other abbreviations.
a
This model was univariate.