Table A3.
Decrease in LVEF by Baseline Markers
| Baseline Marker | Decrease in LVEF* |
P | |
|---|---|---|---|
| Yes | No | ||
| BNP > 40 ng/mL | 3/14 (21%) | 4/49 (8%) | .18 |
| TnT > 0.01 mcg/mL | 0/14 | 0/52 | |
| TnI > 0.04 mcg/mL | 3/14 (21%) | 3/52 (6%) | .10 |
| CRP > 3 mg/L | 6/14 (43%) | 20/53 (38%) | .76 |
| TNF-α > 4.71 pg/mL | 0/14 | 3/53 (6%) | 1.00 |
| IL-6 > 10 pg/mL | 1/14 (7%) | 3/52 (6%) | 1.00 |
| IL-1β > 0.54 pg/mL | 0/13 | 0/47 | |
Abbreviations: BNP, brain natriuretic peptide; CRP, C-reactive protein; IL, interleukin; LVEF, left ventricular ejection fraction; Tn, troponin; TNF, tumor necrosis factor.
*
Decrease in LVEF measure was defined as a decrease of 10% to 15% from baseline to below the lower limit of normal or a decrease in LVEF > 15%.