Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2016 Aug 11.

Published in final edited form as: Wound Repair Regen. 2015 Nov 4;23(6):842–854. doi: 10.1111/wrr.12365

P. aeruginosa biofilms were grown for 48 hours at 30°C on the biological wound dressing prior to treatment with tryptophan (0 – 10 mM). The treatment lasted for an additional 24 hours at 30°C. A) Crystal violet staining revealed that tryptophan significantly inhibited additional biofilm growth (*, p<0.05) and that concentrations above 5mM were not significantly higher than the initial biofilm. B) Quantification of bacterial cells attached to the dressing showed that tryptophan significantly reduced additional bacterial colonization compared to the fresh media alone (*, p<0.05), concentrations of tryptophan above 1mM were not significantly different than the initial bacterial load on the dressing.

P. aeruginosa biofilms were grown for 48 hours at 30°C on the biological wound dressing prior to treatment with tryptophan (0 – 10 mM). The treatment lasted for an additional 24 hours at 30°C. A) Crystal violet staining revealed that tryptophan significantly inhibited additional biofilm growth (*, p<0.05) and that concentrations above 5mM were not significantly higher than the initial biofilm. B) Quantification of bacterial cells attached to the dressing showed that tryptophan significantly reduced additional bacterial colonization compared to the fresh media alone (*, p<0.05), concentrations of tryptophan above 1mM were not significantly different than the initial bacterial load on the dressing.