Table 2. Allelic distribution of HLA class I alleles and their correlation with HCV infection outcome in Chinese population.
| HLA allele | Spontaneous clearance n (%) | Persistent infection n (%) | P (Pc) | OR (95%C.I.) |
|---|---|---|---|---|
| A*02:01 | 47 (10.2) | 52 (6.1) | 0.004 (0.024) | 1.839 (1.212, 2.791) |
| A*02:03 | 33 (7.1) | 65 (7.6) | 0.888 | 0.969 (0.624, 1.504) |
| A*02:07 | 54 (11.7) | 101 (11.8) | 0.883 | 1.027 (0.718, 1.470) |
| A*11:01 | 122 (26.4) | 251 (29.3) | 0.414 | 0.895(0.684, 1.169) |
| A*24:02 | 53 (11.5) | 131 (15.3) | 0.083 | 0.735 (0.519, 1.042) |
| A*33:03 | 51 (11.0) | 89 (10.4) | 0.572 | 1.113 (0.768, 1.612) |
| B*13:01 | 38 (8.2) | 67 (7.8) | 0.581 | 1.129 (0.734, 1.737) |
| B*15:02 | 39 (8.4) | 64 (7.5) | 0.351 | 1.227 (0.797, 1.889) |
| B*40:01 | 55 (11.9) | 137 (16.0) | 0.077 | 0.724 (0.506, 1.036) |
| B*46:01 | 72 (15.6) | 134 (15.6) | 0.689 | 1.072 (0.764, 1.504) |
| B*58:01 | 44 (9.5) | 83 (9.7) | 0.832 | 1.045 (0.699, 1.562) |
| C*01:02 | 87 (18.9) | 173 (20.3) | 0.783 | 0.959 (0.710, 1.295) |
| C*03:02 | 43 (9.3) | 80 (9.4) | 0.84 | 1.042 (0.700, 1.549) |
| C*03:04 | 59 (12.8) | 110 (12.9) | 0.819 | 1.041 (0.735, 1.475) |
| C*06:02 | 29 (6.3) | 42 (4.9) | 0.217 | 1.363 (0.832, 2.231) |
| C*07:02 | 61 (13.3) | 151 (17.7) | 0.062 | 0.729 (0.523, 1.017) |
| C*08:01 | 54 (11.7) | 86 (10.1) | 0.234 | 1.251 (0.865, 1.811) |
Alleles with >5% frequencies are shown at the 4-digit level and analyzed; Pc, Corrected P value for multiple comparisons by Bonferroni correction. Alleles with statistical significance after Bonferroni correction are indicated in bold.