Table 3. Allelic distribution of HLA class II alleles and their correlation with HCV infection outcome in Chinese population.
| HLA allele | Spontaneous clearance n (%) | Persistent infection n (%) | P (Pc) | OR (95%C.I.) |
|---|---|---|---|---|
| DPB1*02:01 | 73 (16.1) | 145 (17.0) | 0.914 | 0.983 (0.716, 1.349) |
| DPB1*02:02 | 24 (5.3) | 52 (6.1) | 0.671 | 0.897 (0.543, 1.482) |
| DPB1*04:01 | 39 (8.6) | 70 (8.2) | 0.643 | 1.103 (0.728, 1.671) |
| DPB1*05:01 | 178 (39.2) | 340 (39.8) | 0.695 | 1.053 (0.812, 1.367) |
| DPB1*13:01 | 29 (6.4) | 65 (7.6) | 0.527 | 0.862 (0.545, 1.364) |
| DQB1*02:01 | 31 (6.7) | 60 (7.0) | 0.651 | 0.901 (0.573, 1.417) |
| DQB1*02:02 | 33 (7.2) | 38 (4.4) | 0.063 | 1.576 (0.972, 2.557) |
| DQB1*03:01 | 121 (26.3) | 167 (19.5) | 0.017 (0.136) | 1.398 (1.060, 1.843) |
| DQB1*03:02 | 27 (5.9) | 46 (5.4) | 0.892 | 1.035 (0.633, 1.693) |
| DQB1*03:03 | 77 (16.7) | 126 (14.7) | 0.579 | 1.093 (0.798, 1.499) |
| DQB1*05:02 | 38 (8.3) | 113 (13.2) | 0.002 (0.016) | 0.547 (0.370, 0.809) |
| DQB1*06:01 | 41 (8.9) | 84 (9.8) | 0.394 | 0.842 (0.567, 1.251) |
| DQB1*06:02 | 22 (4.8) | 52 (6.1) | 0.227 | 0.729 (0.436, 1.220) |
| DRB1*03:01 | 31 (6.7) | 60 (7.0) | 0.626 | 0.893 (0.565, 1.410) |
| DRB1*04:05 | 16 (3.5) | 52 (6.1) | 0.022 (0.176) | 0.514 (0.288, 0.916) |
| DRB1*07:01 | 35 (7.6) | 47 (5.5) | 0.214 | 1.338 (0.844, 2.120) |
| DRB1*08:03 | 23 (5.0) | 44 (5.1) | 0.715 | 0.907 (0.537, 1.531) |
| DRB1*09:01 | 77 (16.7) | 117 (13.6) | 0.281 | 1.197 (0.863, 1.659) |
| DRB1*11:01 | 44 (9.5) | 45 (5.2) | 0.007 (0.056) | 1.820 (1.172, 2.826) |
| DRB1*12:02 | 56 (12.1) | 96 (11.2) | 0.9 | 1.024 (0.713, 1.470) |
| DRB1*15:01 | 43 (9.3) | 107 (12.5) | 0.031 (0.248) | 0.657 (0.448, 0.964) |
Alleles with >5% frequencies are shown at the 4-digit level and analyzed; Pc, Corrected P value for multiple comparisons by Bonferroni correction. Alleles with statistical significance after Bonferroni correction are indicated in bold.