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. 2016 Aug 11;6:31209. doi: 10.1038/srep31209

Figure 2. Expression of immune system related pathway genes are altered in PTSD.

Figure 2

(a) The top 20 canonical pathways selected for finding the genes common in more than one canonical pathway (overlap). Many of the differentially expressed genes are present in multiple pathways related to immune system biology. Table 2 has the list of genes from our dataset that are present in all the canonical pathways in the list. (b) T helper cell differentiation canonical pathway with genes differentially expressed in PTSD. Red and green colors indicate up- and downregulated genes, respectively, in PTSD. The pathway was generated by analyzing all the differentially expressed genes in IPA. (c) The differentially expressed genes were analyzed on Panther pathways analysis tool. The Panther pathway with highest number of genes (10) from the dataset was “inflammation mediated by chemokine and cytokine signaling pathway” (P00031).