Table 1. Demographics and clinical history of the PTSD patients included for the microarray and RNA-Seq analysis.
| For miRNA microarray analysis | |||
|---|---|---|---|
| Parameters | Control (n = 4) | Patient (n = 8) | P-value |
| Age | 40.5 (4.8) | 37.2 (5.3) | 0.323 |
| Race | |||
| AA* | 2 (0.167) | 3 (0.250) | |
| CA** | 2 (0.167) | 4 (0.333) | |
| Hisp*** | 0 (0.000) | 1 (0.083) | 0.571 |
| Depression score | 17 (4.3) | 30.4 (9.6) | 0.008 |
| Anxiety score | 14.8 (12.2) | 29 (11.6) | 0.102 |
| PTSD score | 43.5 (2.1) | 62.9 (12.1) | 0.002 |
| For RNA-Seq analysis | |||
| Parameters | Control (n = 5) | Patient (n = 5) | P-value |
| Age | 42.6 (6.3) | 38.4 (8.8) | 0.414 |
| Race | |||
| AA* | 2 (0.2) | 4 (0.4) | |
| CA** | 3 (0.3) | 1 (0.1) | 0.221 |
| Depression score | 14.4 (6.9) | 38.6 (11.5) | 0.006 |
| Anxiety score | 11.8 (12.4) | 41.2 (13.5) | 0.007 |
| PTSD score | 42.6 (2.7) | 70.8 (13) | 0.007 |
The mean (standard deviation) was used for continuous variable and the number (proportion) was used for categorical variable. Based on t test and Kruskal Wallis test, the age and race were comparable. Gender is not listed since all participants were males. The values indicate mean and the values in parentheses for age, depression, anxiety and PTSD score indicates standard deviation. Depression, anxiety and PTSD scores were determined as per PCL, CAPS and DSM criteria4,50,51.
*African American; **Caucasian; ***Hispanic.