Table 2. Association of SNPs with non-syndromic orofacial cleft susceptibility.

SNP ID	P value for HWE	Allelic Comparison		Co-dominant model				Additive model
		Palla	OR, 95%CI	Phetb	OR, 95%CI	Phomc	OR, 95%CI	Paddd	OR, 95%CI
rs13317	0.474	0.935	0.99 [0.84, 1.18]	0.919	1.01 [0.80, 1.29]	0.859	0.97 [0.66, 1.42]	0.934	0.99 [0.84, 1.18]
rs1476215	0.522	0.414	1.17 [0.80, 1.70]	0.302	1.23 [0.83, 1.81]	0.999	—	0.406	1.18 [0.80, 1.72]
rs1048201	1.000	0.026	0.83 [0.71, 0.98]	0.007	0.70 [0.13, 0.54]	0.049	0.72 [0.17, 0.52]	0.026	0.83 [0.71, 0.98]
rs1047057	0.596	0.342	1.08 [0.92, 1.27]	0.194	1.19 [0.92, 1.53]	0.450	1.14 [0.81, 1.59]	0.337	1.08 [0.92, 1.28]
rs4690150	0.253	0.49	0.94 [0.80, 1.11]	0.785	0.97 [0.75, 1.25]	0.457	0.88 [0.18, 0.62]	0.482	0.94 [0.80, 1.11]
rs6838203	0.852	0.469	1.06 [0.90, 1.26]	0.039	1.30 [1.01, 1.67]	0.952	0.99 [0.69, 1.42]	0.468	1.06 [0.90, 1.26]
rs3733336	0.181	0.001	0.73 [0.60, 0.88]	0.013	0.74 [0.28, 0.83]	0.008	0.48 [0.28, 0.83]	< 0.001	0.72 [0.59, 0.87]
rs2241286	0.009	—	—	—	—	—	—	—	—
rs546782	0.509	0.040	0.57 [0.33, 0.98]	0.066	0.60 [0.34, 1.04]	—	—	0.043	0.57 [0.33, 0.98]
rs3176304	1.000	0.689	1.04 [0.86, 1.26]	0.287	1.14 [0.90, 1.45]	0.613	0.88 [0.53, 1.46]	0.689	1.04 [0.86, 1.26]

SNP, single nucleotide polymorphism; Chr, chromosome; OR, odds ratio; 95%CI, 95% confidence interval.

^aP value of allelic comparison; rs1048201- T vs. C, rs3733336- G vs. A, rs546782-T vs. A.

^bP value of heterozygous comparison; rs1048201 - CT vs. CC, rs3733336 - AG vs. AA, rs546782 - AT vs. AA.

^cP value of homozygous comparison; rs1048201 - TT vs. CC, rs3733336 - GG vs. AA, rs546782-TT vs. AA.

^dP value of additive model analysis.