Table 3. Distribution of VHLdb interactors and mutations by pVHL interacting surface.

Surface	Start	End	Interactors	Mutations
A	T154	D189	9	190
B	P60	R109	41	254
C	P104	I153	6	284
D	M1	R59	1	99
Unknown			55	280
Upon modification			5
Total			117	1074

For each surface, start and end residues as well as the number of interactors and mutations are reported. The “upon modification’’ row indicates the number of proteins which bind the pVHL protein after it has been phoshorylated in some residue.