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. 2016 Aug 11;6:31304. doi: 10.1038/srep31304

Figure 5. The impact of carbon nanotube treatments on cell viability, reactive oxygen species (ROS) and miR-21 expression.

Figure 5

(A) Schematic procedure of carbon nanotube treatments for microtissue experiments. (B) Cell viability test in 2D culture after treatment with different carbon nanotube groups. S-MWCNT-C at 5 μg/ml caused severe cell death. The treatment of MWCNT and S-MWCNT-C at 50 ng/mL showed mild cytotoxicity. (C) Cell viability test in microtissues after treatment with carbon nanotubes. (D) ROS measurement in 2D culture; (E) ROS measurement in microtissue; (F) miR-21 expression after carbon nanotube exposure. The treatment of MWCNT and S-MWCNT-C at 50 ng/mL caused substantial increase in miR-21 expression level.