TABLE 3.
Pathologic characteristics of prostate cancer patients with seminal vesicle invasion following radical prostatectomy at University of Pennsylvania, 1990–2012.
| Caucasian Cohort n=41 |
% | African-American Cohort n=23 |
% | p- Value | |
|---|---|---|---|---|---|
| iPSA ng/ml | 0.02 | ||||
| 0–4.0 | 4 | 10 | 1 | 5 | |
| 4.1–10 | 22 | 56 | 8 | 36 | |
| 10.1 – 20 | 12 | 31 | 7 | 32 | |
| > 20 | 1 | 3 | 6 | 27 | |
| median | 6.5 | 12.3 | |||
| mean | 9.4 | 17 | |||
| IQR | 4.6 –11.6 | 7 –22 | |||
|
| |||||
| Prostate Size | 0.3 | ||||
| <50cc | 20 | 56 | 14 | 70 | |
| >50cc | 16 | 44 | 6 | 3 | |
| median | 47.7 | 45 | |||
| mean | 52 | 47 | |||
| IQR | 41 –56 | 34 – 56 | |||
|
| |||||
| Gland involvement (%) | 0.8 | ||||
| <10 | 10 | 27 | 4 | 18 | |
| 10 to 25 | 10 | 27 | 8 | 36 | |
| 25 to 50 | 10 | 27 | 7 | 32 | |
| > 50 | 7 | 19 | 3 | 14 | |
|
| |||||
| Seminal vesicle invasion | 0.3 | ||||
| Unilateral | 26 | 67 | 18 | 78 | |
| Bilateral | 13 | 33 | 5 | 22 | |
|
| |||||
| Extraprostatic spread | 0.4 | ||||
| Yes | 37 | 90 | 19 | 83 | |
| No | 4 | 10 | 4 | 17 | |
|
| |||||
| Positive Surgical Margins | 0.7 | ||||
| Yes | 21 | 51 | 10 | 45 | |
| No | 20 | 49 | 12 | 55 | |
NOTE. Boldfaced values represent statistically significant differences between groups.
Abbreviations: iPSA- initial Prostate-specific antigen, IQR- interquartile range.