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Synthesis of tetrahydro-betacarboline-hydantoin derivatives. Reagents and conditions: (a) ethyl or butyl or t-butyl or allyl isocyanate, 2-butanone, reflux, under N2 atmosphere, 16–70 h, 25–87.2%; R = –C2H5 or –(CH2)3CH3 or –C–(CH3)3 or –CH2–CH=CH2. For exact individual assignment, see Table 2.
