Table 1.
Tumour models
| Tumour | Type | Origin | Model type | Host (supplier) | |
|---|---|---|---|---|---|
| CRUK Cambridge Institute (CI) | AsPC-1 | Pancreatic | Human | Xenografta | CB17 SCID mouse (Charles River) |
| MiaPaCa-2 | Pancreatic | Human | Xenografta | CB17 SCID mouse (Charles River) | |
| PancTu I | Pancreatic | Human | Xenografta | CB17 SCID mouse (Charles River) | |
| Colo-357 | Pancreatic | Human | Xenografta | CB17 SCID mouse (Charles River) | |
| K8484b | Pancreatic | Murine | Syngeneic allografta | PC mouse (p53R172H; Pdx1-Cre) (CI) | |
| KPCc | Pancreatic | Murine | Spontaneousd | KPC mouse (KrasG12D; p53R172H; Pdx1-Cre) (CI) | |
| AstraZeneca (AZ) | PC9 | NSCLC | Human | Xenografta | CB17 SCID mouse (AstraZeneca) |
| A431 | Squamous carcinoma | Human | Xenografta | ONU mouse (AstraZeneca) | |
| H1975 | NSCLC | Human | Xenografta | ONU mouse (AstraZeneca) | |
| Imperial College London (IC) | HCT116 | Colorectal | Human | Xenografta | BALB/c nu mouse (Charles River) |
| WWU Münster | A549 | NSCLC | Human | Xenografta | NMRI nu mouse (Janvier) |
| HTB56 | NSCLC | Human | Xenografta | NMRI nu mouse (Janvier) | |
| EBC1 | NSCLC | Human | Xenografta | NMRI nu mouse (Janvier) | |
| H1975 | NSCLC | Human | Xenografta | NMRI nu mouse (Janvier) | |
| WMIC Manchester | MDA-MB-231-MFP | Breast | Human | Xenografte | CBA nu/nu mouse (University of Manchester) |
| A549 | NSCLC | Human | Xenografta | CBA nu/nu mouse (University of Manchester) | |
| HCT116 | Colorectal | Human | Xenografta | CBA nu/nu mouse (University of Manchester) | |
| A2870 | Ovarian carcinoma | Human | Xenografta | CBA nu/nu mouse (University of Manchester) | |
| U87 | Glioblastoma | Human | Xenografta | CBA nu/nu mouse (University of Manchester) | |
| FTC113 | Follicular thyroid carcinoma | Human | Xenografta | CBA nu/nu mouse (University of Manchester) | |
| KHT | Sarcoma | Murine | Syngeneic autografta | C3H mouse (University of Manchester) | |
| Radboudumc Nijmegen | CC531 | Colorectal | Rodent | Syngeneic liver metastasisf |
Wag/Rij rats (Charles River) |
aSubcutaneous tumours
b[15]
cHingorani SR, Wang L, Multani AS, Combs C, Deramoudt TB, Hruban RH et al. Trp53R172H and KRASG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer cell. 2005;7(5):469–483
dSpontaneous tumours arising in the pancreas
eOrthotopic tumours (mammary fat-pad implant)
fTumours created by intra-hepatic injection