Table 3.

Multivariate survival analysis of patients stratified according to 8 cycles of treatment for overall survival

	Univariate COX regression			Multivariats logistic regression
	Hazard ratio	95 % Cl	p value	Hazard ratio	95 % Cl	p value
Sex (man vs woman)	1.13	0.62–2.04	0.7
Age (≥70 years vs <70 years)	1.22	0.65–2.23	0.53
T stage (4 vs 1–3)	1.77	0.79–3.97	0.17	1.21	0.51–2.89	0.67
N stage (2 vs 1)	1.31	0.73–2.37	0.37
Histo-pathological grade (poor differentiated vs. well, moderated differentiated)	1.51	0.78 –5.23	0.35
Site (right vs left)	1.1	0.61–1.98	0.76
Pre-operative CEA (≥ 5 vs. < 5)	0.9	0.46–1.75	0.76
Performance status (1 and 2 vs.0)	2.08	0.93–4.66	0.08	1.91	0.83–4.40	0.13
FOLFOX cycles (≥8 vs <8)	0.54	0.30–0.99	0.043	0.52	0.28–0.97	0.038
Lymph nodes (≥12 vs. <12)	3.1	0.75–12.89	0.12	2.9	0.68–12.31	0.15
Time to treatment (≥8 vs <8 weeks)	1.71	0.61–4.79	0.31
Perforation or obstruction	1.92	0.99–3.73	0.053	1.41	0.68–2.93	0.36