Table 26.
Meta-analysis of Liver Stiffness Progression Rates (LSPR) in Chronic HCV infection.
| N | Fixed Effect | Random Effects | I 2 | |||
|---|---|---|---|---|---|---|
| Meta-Analysis | Meta-Analysis | |||||
| LSPR (kPa/yr) | 95% CI | LSPR (kPa/yr) | 95% CI | |||
| All studies | ||||||
| Indirect | 31 | 0.091 | 0.085–0.098 | 0.141 | 0.115–0.166 | 92% |
| Direct | 8 | 0.099 | 0.067–0.131 | 0.137 | 0.069–0.205 | 47% |
| HCV monoinfected | ||||||
| Indirect | 13 | 0.082 | 0.072–0.092 | 0.100 | 0.073–0.128 | 83% |
| Direct | 3 | 0.083 | 0.049–0.116 | 0.085 | 0.040–0.129 | 27% |
| HIV/HCV coinfected | ||||||
| Indirect | 16 | 0.097 | 0.088–0.105 | 0.167 | 0.127–0.208 | 94% |
| Direct | 5 | 0.261 | 0.155–0.367 | 0.261 | 0.155–0.367 | 0% |